ABSTRACT
AbstractJorge Lobo's Disease is a rare, chronic granulomatous cutaneous mycosis, which is typical of tropical and subtropical regions. It is caused by the traumatic implantation of the fungus Lacazia loboi into the skin and subcutaneous tissue. The disease was first described in 1931 by Jorge Lobo, in Recife (PE), Brazil. It is common in Central and South America, and predominates in the Amazon region. We report a case of Jorge Lobo's Disease, which had been initially referred as being paracoccidioidomycosis. We emphasize clinical and diagnostic features of the disease.
Subject(s)
Humans , Male , Middle Aged , Lacazia/growth & development , Lobomycosis/microbiology , Lobomycosis/pathology , Skin/microbiology , Skin/pathology , Brazil , Rare Diseases/microbiology , Rare Diseases/pathologyABSTRACT
Subcutaneous fat necrosis of the newborn is an unusual form of panniculitis, with few cases described in medical literature. The disease affects newborns at term or post-term, with normal general health. We describe two cases of newborns affected by the disease. One of them already had lesions since birth. Also, we discuss the use of puncture for diagnostic assistance.
A Necrose Gordurosa Subcutânea do Recém-Nascido é uma paniculite incomum com poucos casos descritos na literatura médica. A doença acomete recém-nascidos a termo ou pós-termo, com saúde geral normal. Relatamos dois casos de recém-nascidos acometidos pela doença. Um deles já apresentava lesões ao nascer. Também discutimos o uso da punção para auxílio diagnóstico.
Subject(s)
Female , Humans , Infant, Newborn , Male , Fat Necrosis/pathology , Subcutaneous Fat/pathology , Biopsy, Fine-Needle , Panniculitis/pathology , Skin/pathologyABSTRACT
The authors proposed a systematic review on the current concepts of primary neural leprosy by consulting the following online databases: MEDLINE, Lilacs/SciELO, and Embase. Selected studies were classified based on the degree of recommendation and levels of scientific evidence according to the “Oxford Centre for Evidence-based Medicine”. The following aspects were reviewed: cutaneous clinical and laboratorial investigations, i.e. skin clinical exam, smears, and biopsy, and Mitsuda's reaction; neurological investigation (anamnesis, electromyography and nerve biopsy); serological investigation and molecular testing, i.e. serological testing for the detection of the phenolic glycolipid 1 (PGL-I) and the polymerase chain reaction (PCR); and treatment (classification criteria for the definition of specific treatment, steroid treatment, and cure criteria).
.Os autores propuseram-se a realizar uma revisão sistemática em conceitos atuais sobre a hanseníase neural primária, consultando as seguintes bases bibliográficas
Subject(s)
Humans , Leprosy, Tuberculoid/diagnosis , Leprosy, Tuberculoid/therapy , Biopsy/methods , Diagnosis, Differential , Evidence-Based Medicine , Leprosy, Tuberculoid/physiopathology , Neural Conduction/physiology , Neurons/pathology , Sensitivity and Specificity , Skin/pathologyABSTRACT
Primary cutaneous plasmacytoma is a rare disease characterized by monoclonal proliferation of plasma cells in the skin, in the absence of bone or systemic disease. It can be solitary or multiple, the latter being even more rare and presenting a higher mortality rate. We describe the clinical, histopathological and immunohistochemical aspects as well as the evolution of an 87-year-old female patient, diagnosed as having multiple primary cutaneous plasmacytomas.
O plasmocitoma cutâneo primário é uma entidade rara, caracterizada pela proliferação monoclonal de plasmócitos na pele, na ausência de doença óssea ou sistêmica. Pode ser único ou múltiplo, sendo esta última forma ainda mais rara e de pior prognóstico. Descreveremos os aspectos clínicos, histopatológicos, imunohistoquímicos e a evolução de um caso de paciente do sexo feminino, 87 anos, com diagnóstico de plasmocitoma cutâneo primário com múltiplas lesões.